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6th Annual SoCal CryoEM Symposium
The 6th Annual Southern California Cryo-Electron Microscopy Symposium will be held online on Friday, October 29th, 2021, bringing together electron microscopists in Southern California focused on studying the fundamental mechanisms of biological systems.

9:00 AM - 9:05 AM Introduction
9:05 AM - 10:05AM CryoEM Technological Advancements Talks (10 + 3 min Q&A)
9:05 - 9:20 Geoffrey Woollard (University of British Columbia) Why cryoEM practitioners should learn more math and theory, and how to do it.
9:20 - 9:35 Maxwell James Bachochin (UCSD) To 2D, or not to 2D (classify), that is the question
9:35 - 9:50 Aleksandar Antanasijevic (Scripps) From Structure to Sequence: Antibody discovery using cryoEM
9:50 - 10:05 Sara Weaver (UCLA) Ab initio phasing macromolecular structures using electron-counted MicroED data
10:05 AM - 10:15 AM Nicole Poweleit from NanoImaging Services Vendor Talk: Industry applications of Cryo EM at NanoImaging Services
10:15 AM - 11:15 AM Tomography and Cellular Studies Talks (10 + 3 min Q&A)
10:15 - 10:30 Wei Zhao (Caltech) In situ architecture of human kinetochore-microtubule interface visualized by cryo-electron tomography
10:30 - 10:45 Mohammed Kaplan (Caltech) Novel transient cytoplasmic rings stabilize assembling bacterial flagellar motors
10:45 - 11:00 Ben Barad (Scripps) Modeling the complex geometry of organelle membranes in cells with cryo-electron tomography
11:00 - 11:15 Shervin Nia (UCLA) Charting alkaline dissolution of cell-grown insecticidal pro-toxin cry11b crystals by time-series cryo-electron tomography
11:15 AM - 11:25 AM Blanca Carbajal Gonzalez from Thermo Fisher Scientific Vendor Talk: Inspection & Verification of Fluorescent Targets using the Aquilos 2 Cryo DualBeam
11:25 AM - 12:40 PM Posters and Lunch
12:40 PM - 2:10 PM Single-Particle & MicroED Applications Talks (10 + 3 min Q&A)
12:40 - 12:55 Yao He (UCLA) Structures of telomerase at several steps of telomere repeat synthesis
12:55 - 1:10 Mariusz Matyszewski (UCSD) A Tale of Two Filaments: Binding Mechanism of a Right-Handed LRRK2 Filament to a Left-Handed Microtubule
1:10 - 1:25 Karen Orta (Caltech) Structural insights behind phage single-gene lysis protein E
1:25 - 1:40 Maria Flores (UCLA) CryoEM structure of human CPEB3's reversible prion-like domain
1:40 - 1:55 Yi Xiao (Sean) Jiang (UCLA) Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) are composed of TMEM106B, rather than TDP-43
1:55 - 2:10 Randy Watson (Scripps) Conformational Control of Cereblon
2:10 PM - 2:20 PM Michael Spilman from Direct Electron Vendor Talk: Apollo - a new event-based detector for ultrafast CryoEM
2:20 PM - 3:05 PM SoCal Workshop Figure preparation techniques in Adobe Illustrator/Photoshop for structural biologists with Hailee Perrett
3:05 PM - 3:15 PM Joyce Frank from Mitegen Vendor Talk: Technologies and Developments in Cryo-EM
3:15 PM - 4:15 PM Keynote Session The Future of CryoEM: Protein structural biology in the era of high-accuracy structure prediction. Presenter: Benjamin Basanta Panelists: Mark Herzik, Jose Rodriguez and Elizabeth Villa
4:15 PM - 4:25 PM Closing Remarks, Poster & Art Prizes
4:25 PM - 4:55 PM Virtual Vendor Booths
4:55 PM - 5:30 PM Networking Event